Nimesulide Tablet Uses: What You Need to Know

Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) prescribed primarily for pain management in India. This article explains its approved applications, safety considerations, and how it works.

Approved Medical Uses of Nimesulide Tablets

Acute Pain Treatment Used for short-term relief of:

Postoperative pain
Dental pain (tooth extraction)
Musculoskeletal pain (strains/sprains)
Ear, nose, and throat-related pain

Osteoarthritis Pain Manages pain and inflammation in degenerative joint disease cases
Primary Dysmenorrhea Prescribed for severe menstrual cramps unresponsive to other NSAIDs

How Nimesulide Works

Inhibits COX-2 enzymes to reduce prostaglandin production
Provides analgesic (pain-relieving) and antipyretic (fever-reducing) effects
Shows anti-inflammatory properties within 15-30 minutes

Standard Dosage in India

Adults (12+ years):

100mg twice daily after meals
Maximum daily dose: 200mg
Maximum treatment duration: 15 days

Not approved for:

Children below 12 years
Pregnant/lactating women
Chronic pain conditions

Important Safety Precautions

Liver Health

Avoid with pre-existing liver conditions
Discontinue if nausea/vomiting persist
Monitor liver enzymes during prolonged use

Contraindications

History of gastrointestinal bleeding
Kidney disease patients
Heart disease patients
Aspirin-sensitive asthma

Drug Interactions

Blood thinners (warfarin)
Other NSAIDs
Diuretics
Lithium

Common Side Effects

Heartburn/indigestion (most common)
Dizziness
Skin rashes
Mild nausea

When to Stop Medication Immediately

Contact your doctor if experiencing:

Dark urine
Yellowing of eyes/skin
Severe abdominal pain
Unexplained fatigue

Alternatives to Nimesulide

Common substitutes prescribed in India:

Aceclofenac
Paracetamol combinations
Etoricoxib

Regulatory Status in India

Approved for use in patients above 12 years
Banned in liquid formulations for children
Requires prescription
Banned in several countries due to hepatotoxicity risks

Frequently Asked Questions

Can nimesulide cure fever? Yes, it has antipyretic properties but isn't first-line treatment for fever.

Is nimesulide banned in India? No, tablets remain approved for adults with restricted dosage limits.

How quickly does it work? Pain relief typically begins within 30-60 minutes.

Can I take it empty stomach? Not recommended - always take after food to reduce gastric irritation.

Important: Nimesulide requires medical supervision. Do not self-medicate or exceed prescribed duration. India's drug authorities recommend using lowest effective dose for shortest possible time.

Consult your physician before starting or stopping this medication.